Brief information about it:
Tenofovir alafenamide (TAF) is a newer formulation of tenofovir, a nucleoside reverse transcriptase inhibitor (NRTI) used to treat HIV/AIDS.
Uses:
Treatment of HIV-1 infection
Mechanism of action:
TAF is a prodrug that is converted to tenofovir in the body, where it interferes with the HIV virus’s ability to replicate.
Elimination half life:
Approximately 17 hours
Route of Administration:
Oral (tablets)
Side effects:
Common side effects include:
- Diarrhea
- Nausea
- Headache
- Fatigue
Dose:
The dosage of TAF varies depending on the individual and the specific treatment regimen. It’s often used in combination with other antiretroviral drugs.
Precautions:
· Kidney function monitoring
· Potential for bone mineral density loss
