Brief information about it:
Lopinavir/ritonavir is a combination drug used to treat HIV/AIDS. It combines two antiretroviral medications: lopinavir, a protease inhibitor, and ritonavir, a drug that boosts the levels of lopinavir in the body.
Uses:
Treatment of HIV/AIDS
Mechanism of action:
· Lopinavir: Inhibits HIV protease, preventing the virus from maturing and infecting new cells.
· Ritonavir: Boosts the levels of lopinavir in the body, increasing its effectiveness.
Elimination half life:
Approximately 3-5 hours for both drugs.
Route of Administration:
Oral (capsules, solution)
Side effects:
Common side effects include:
- Diarrhea
- Nausea
- Vomiting
- Headache
- Fatigue
- Changes in body fat distribution
- Liver problems
- Pancreatitis
- Kidney problems
Dose:
The dosage varies depending on the individual and specific treatment regimen. It’s crucial to follow prescribed dosage and consult with a healthcare provider.
Precautions:
· Liver function monitoring
· Potential for drug interactions
· Risk of metabolic side effects
