Brief information about it:
Efavirenz is an antiretroviral medication used to treat HIV/AIDS.
Uses:
Treatment of HIV/AIDS: It is used in combination with other antiretroviral drugs to slow the progression of HIV infection and reduce the risk of opportunistic infections.
Mechanism of action:
Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by directly blocking the HIV reverse transcriptase enzyme, preventing the virus from replicating.
Elimination half life:
The half-life of efavirenz is approximately 40-55 hours.
Route of Administration:
Efavirenz is typically administered orally in tablet form.
Side effects:
Common side effects of efavirenz include:
- Dizziness
- Drowsiness
- Fatigue
- Rash
- Nervous system symptoms (e.g., difficulty concentrating, vivid dreams)
More serious side effects, although rare, can include:
- Liver damage
- Psychiatric disorders
- Stevens-Johnson syndrome (a severe skin reaction)
Dose:
The dosage of efavirenz varies depending on the individual and the specific treatment regimen. It is important to follow the prescribed dosage and consult with a healthcare provider for any adjustments.
Precautions:
· Nervous System Effects: Efavirenz can affect the nervous system, leading to dizziness, drowsiness, and difficulty concentrating. It’s important to avoid driving or operating machinery until you know how efavirenz affects you.
· Liver Function: Efavirenz can affect liver function, so regular monitoring of liver enzymes is necessary.
· Psychiatric Effects: Efavirenz can cause psychiatric side effects, such as depression, anxiety, and unusual dreams.
· Drug Interactions: Efavirenz can interact with other medications, so it’s important to inform your healthcare provider about all medications you are taking.
