Brief information about it:
Tenofovir is an antiretroviral medication used to treat HIV/AIDS.
Uses:
· Treatment of HIV/AIDS: It is used in combination with other antiretroviral drugs to slow the progression of HIV infection and reduce the risk of opportunistic infections.
· Prevention of Mother-to-Child Transmission (PMTCT): Tenofovir is used to prevent the transmission of HIV from an infected mother to her child during pregnancy, childbirth, or breastfeeding.
Mechanism of action:
Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI). It works by interfering with the HIV virus’s ability to replicate itself. It does this by mimicking a building block of DNA, tricking the virus into incorporating it into its genetic material. This ultimately stops the virus from replicating.
Elimination half life:
The half-life of tenofovir varies depending on the specific formulation.
Route of Administration:
Tenofovir is typically administered orally in tablet form.
Side effects:
Common side effects of tenofovir include:
- Kidney problems
- Loss of bone mineral density
- Lactic acidosis
Dose:
The dosage of tenofovir varies depending on the individual and the specific treatment regimen. It is important to follow the prescribed dosage and consult with a healthcare provider for any adjustments.
Precautions:
· Kidney Function: Tenofovir can affect kidney function, so regular monitoring of kidney function is necessary.
· Bone Health: Tenofovir can lead to bone loss, especially in long-term use.
· Drug Interactions: Tenofovir can interact with other medications, so it’s important to inform your healthcare provider about all medications you are taking.
