Brief information about it:
Dolutegravir is an integrase inhibitor (INHI) medication used to treat HIV/AIDS.
Uses:
· Treatment of HIV/AIDS
· Prevention of Mother-to-Child Transmission (PMTCT)
Mechanism of action:
Dolutegravir inhibits the integrase enzyme, preventing the HIV virus from integrating its genetic material into the host cell’s DNA.
Elimination half life:
Approximately 14 hours
Route of Administration:
Oral (tablets)
Side effects:
Common side effects include:
- Headache
- Fatigue
- Insomnia
- Diarrhea
- Nausea
- Rash
Dose:
The dosage of dolutegravir varies depending on the individual and the specific treatment regimen. It’s crucial to follow prescribed dosage and consult with a healthcare provider.
Precautions:
· Potential for neurological side effects, especially in individuals with certain genetic factors
· Drug interactions
