Integrase Inhibitors (IIs)

Raltegravir:
Brief information about it:
Raltegravir is an integrase inhibitor (INHI) medication used to treat HIV/AIDS.
Uses:
Treatment of HIV/AIDS
Mechanism of action:
Raltegravir inhibits the integrase enzyme, preventing the HIV virus from integrating its genetic material into the host cell’s DNA.
Elimination half life:
Approximately 7-9 hours
Route of Administration:
Oral (tablets)
Side effects:
Common side effects include:
- Headache
- Dizziness
- Fatigue
- Insomnia
- Nausea
- Diarrhea
Dose:
The dosage of raltegravir varies depending on the individual and the specific treatment regimen. It’s crucial to follow prescribed dosage and consult with a healthcare provider.
Precautions:
· Potential for drug interactions
· Risk of hypersensitivity reactions