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Post-Exposure Prophylaxis (PEP): Reducing the Risk of HIV Transmission

What is PEP?

  • Post-exposure prophylaxis (PEP) is a medication regimen taken after a potential exposure to HIV to prevent infection.  
  • It’s a short-term course of antiretroviral medications, typically taken for 28 days.  

When Should PEP Be Considered?

  • PEP should be considered as soon as possible, ideally within 72 hours (3 days) of a potential HIV exposure. The sooner PEP is started, the more effective it is.  
  • Situations that may warrant consideration for PEP include:
    • Unprotected sexual intercourse (vaginal, anal, or oral)  
    • Occupational exposure (healthcare workers)  
    • Sharing needles or syringes  
    • Sexual assault  

How PEP Works

  • PEP works by preventing the HIV virus from establishing itself in the body.  
  • The medications in PEP interfere with the virus’s ability to replicate and spread.  

Accessing PEP

  • Seek Medical Attention Immediately: If you believe you may have been exposed to HIV, seek medical attention immediately.
  • Emergency Rooms: Emergency rooms are typically equipped to provide immediate PEP evaluation and initiation.  
  • Healthcare Providers: You can also contact your primary care physician, a sexual health clinic, or an emergency room for guidance.  

Important Considerations:

  • Time is Critical: Starting PEP as soon as possible after exposure is crucial for its effectiveness. Every hour counts.  
  • PEP is not a guarantee against HIV infection.  
  • PEP involves potential side effects: Like any medication, PEP can have side effects.  
  • PEP is not a substitute for consistent use of condoms and other safer sex practices.

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